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Description
Although increasing the cohort size above six results in little increase in the probability of observing a given event, the higher the sample size the greater the probability for observing an event that is not due to a study drug but is simply part of the spontaneous event rate for that event
Hurley TD, Bosron WF, Hamilton JA, Amzel LM
doi: 10.1097/01.ju.0000107838.33623.19
Said SI, Mutt V: Polypeptide with broad biological activity: isolation from small intestine
