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Lack of it is common in women with PCOS and has a connection with insulin resistance, ovulatory issues, and infertility

doi: 10.1111/ene.12297 189 RubegniA.BattistiC.TessaA.CeraseA.DocciniS.MalandriniA.et al

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Most neurons containing agmatine were located in the hypothalamus, forebrain, and cerebral cortex (77), which played important roles in visceral and neuroendocrine control, pain perception, emotion, and cognition (77, 79)