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Yes IGF-1 LR3 has significant insulin-like effects due to structural homology with insulin, causing direct activation of insulin receptors in addition to IGF-1 receptors
Furthermore, multifunctional platforms combining photothermal ablation, ROS modulation, and immunotherapy exhibit promise in overcoming multidrug resistance and reprogramming immunosuppressive microenvironments
Morphological and Structural Characterization 3.2.1

Leenhouwers JI, Knol EF, de Groot PN, Vos H, van der Lende T
