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4a and Extended Data Fig

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elegans, a reduction in GSH and an increase in ferrous iron typically occur in late life, and suppression of ferroptosis using lipid peroxidation inhibitor liproxstatin or iron chelator salicylaldehyde isonicotinoyl hydrazone has been shown to protect against GSH depletion toxicity, dramatically restrain age-related cell death, and improve the lifespan and healthspan of C

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