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In addition, Pycnogenol s antioxidant effects were shown by a significant decrease of 15-F 2t -Isoprostane, a marker of lipid peroxidation from 0.71 0.09 pg/ml to 0.66 0.13 pg/ml, with no change in the placebo group

Looking ahead, establishing collaborative research platforms and promoting active engagement among experts across diverse fields will be key to driving future advancements in target discovery

Moreover, the clinical trials of PF06649751 (NCT02847650 and NCT02687542), GZ/SAR402671 (NCT02906020), CEP-1347 (NCT00040404), ABBV-0805 (NCT04127695), and BIIB054 (NCT03318523), spheramine (NCT00206687), and neuronal progenitor stem cell (NCT00927108) therapy were discontinued due to various reasons (Figure 5)

(PubMed) Choudhury A, Jena A, Jearth V, et al