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Considering prebiotics, i.e., plant-derived fibers such as Oligo-fructose, Isomaltosextrin or Inulin oligofructose, their supplementation showed beneficial effects in improving gut barrier function, in reducing circulating endotoxin levels, in improving glycaemic status and lipid profiles, both in mice and human models [71]

As bacteria in the small intestine ferment the lactulose, they produce gases that are absorbed into the bloodstream and exhaled through the lungs

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Their synoptic interpretation allows proposing a chemically plausible unified mechanism for the production of oxidative stress from electrochemically silent metal ions