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We propose that LPLA2 first transiently interacts with the inner leaflet of the lysosomal membrane via favourable electrostatic 27 and hydrophobic interactions mediated by its membrane-binding domain (Fig

The Nle residue (replacing Met) eliminates the methionine oxidation pathway present in native alpha-MSH

Lucy Norris, a 5 th year veterinary student at the University of Liverpool who carried out the project work, said: I was acutely aware of campaigns by the RSPCA and others raising awareness of the rise in reported cases of ear cropping