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This is supported by metabolomic profiling studies that have identified complex lipid species and amino acid analogues associated with the response to weight loss interventions

Notably, restoration of up to 75% cystine levels in the diet of Cth / CysF mice that were undergoing weight loss was sufficient to completely rescue the body weight over three weight-loss cysteine-depletion cycles, demonstrating the specificity and essentiality of cysteine for the organism (Fig

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