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To counteract amyloid fibril formation that occurs with human Amy, a pair of helix-stabilizing mutations (N14E and V17R) were incorporated into Cagri 2
Cancer-Associated Fibroblasts Recruitment of cancer-associated fibroblasts CAFs are activated by growth factors released from tumor and inflammatory cells, including TGFb, PDGF, and FGF (169, 278, 279)

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