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If hepatocyte loss is great, there may be insufficient liver tissue to release aminotransferases, which may result in decreased instead of increased serum levels of aminotransferases

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The basic circuits of reflex neural control elicited from the gut lumen consist of 1 ) intrinsic primary afferent (intrinsic sensory) neurons that project to the mucosa, where they are activated by an epithelial sensor, since enteric nerves do not project into the epithelium, but lie beneath it