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10.1016/j.biopha.2023.115652 152 SongY

These numbers explain why tirzepatide has generated extraordinary demand and why the dosing protocols follow such a careful titration schedule: you start at 2.5 mg weekly for four weeks, increase to 5 mg, then continue stepping up through 7.5 mg, 10 mg, 12.5 mg, and potentially 15 mg depending on clinical response and tolerability

The cognitive behavioral approach is also recognized as beneficial for patients with fibromyalgia, although it requires expert support that is very rarely available in our public health system
