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Rayatpour A, Foolad F, Heibatollahi M, Khajeh K, Javan M
Endogenous hydrogen sulfide improves vascular remodeling through PPAR/SOCS3 signaling
Pathway-level analysis focuses on identifying metabolic pathways and their activity levels within individual cells by integrating transcriptomic data with prior knowledge of metabolic networks
As ROS are a known inhibitor of mTOR activation, they showed that intracellular GSH was able to buffer ROS leading to mTOR activation, metabolic reprogramming, and resultant inflammatory response of T cells in vitro and in vivo (45)
