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GSH is synthetized in vivo with two ATP-dependent steps where -glutamylcysteine is synthetized by the rate limiting enzyme glutamatecysteine synthase

Comparison and validation of the 2022 European LeukemiaNet guidelines in acute myeloid leukemia

The rate of GTP hydrolysis is often accelerated due to the actions of another family of allosteric modulating proteins called regulators of G-protein signaling, or RGS proteins, which are a type of GTPase-activating protein, or GAP
