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The study that assessed the impact of THC on rodent lifespan was conducted by the US National Toxicology Program (NTP) [129, 130]

Many MCAS patients have impaired pathways for converting glutamate into calming GABA, leading to "glutamate excitotoxicity"which can manifest as severe anxiety, insomnia, heart palpitations, and brain fog

J Pharm Sci 108:29822993

are deficient
