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Therefore, patients' liver function should be closely monitored, and patients who clearly respond to PN should continue with PN therapy, and the addition of the PNPO cofactor riboflavin may improve the activity of residual PNPO [14]

Isoniazid (INH), a tuberculosis medication, and hydralazine, used for hypertension, both form complexes with pyridoxal 5-phosphate or otherwise interfere with vitamin B metabolism, leading to functional vitamin B deficiency

[DOI] [PMC free article] [PubMed] [Google Scholar] 50.Schucht P, Raineteau O, Schwab OE, Fouad K

Alzheimer Res ., 16 , 622632
