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Direct injection of formulations containing 0.5% H 2 O 2 radiosensitized tumors by reoxygenation [237], while engineered systems like lactate oxidase nanocapsules converted immunosuppressive lactate into immunostimulatory H 2 O 2 , sensitizing tumors to anti-PD-1 therapy [238]

Why the Other Choices Are Wrong Internal validity is the degree to which a study accurately measures what it intends to measure within its sample, minimizing systematic errors