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[DOI] [PMC free article] [PubMed] [Google Scholar] 33.Prata JC

In fact, the gln/glu ratio is most prominently increased in patients with schizophrenia as compared with the controls at a young age and seems to normalize in older patients This may reflect a deficiency in glutaminase, the enzyme that converts glutamine into glutamate, which results in reduced glutamate levels and increased glutamine levels in the frontal region

These symptoms are usually mild and go away with time
COXs are abundantly expressed in neurons and microglia across various animal species (Khan et al., 2022)