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Genes associated with this metabolite were retrieved from the GeneCards database and cross-referenced with differentially expressed genes from the GEO database, leading to the identification of 10 candidate biomarker genes: ACSL1, PYGL, DYSF, MGAM, SLC7A7, SULF2, KCNJ2, CYP1B1, NCF2, and SLC22A4

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These findings demonstrate that BM-PCa thrive under oxidative stress conditions and such that regulation of ROS and glutathione programming could be leveraged for targeting of BM-PCa progression.