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Recently, the presence of nuclear-encoded transcription factors (MOF, AP1, CEBPB, MEF2D), and the contribution of nuclear spliceosome complex to mtDNA-splicing provided strong evidence of control of mitochondrial replication/transcription demonstrating evolutionary adaptation of the mammalian mtDNA in the nucleoid [75]

Organ expression of PPAR types is summarized in Table 2

Other strategies are the adding of an additional stage to the STP

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