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Description
Its sequence stability and robust purity profile allow researchers to obtain repeatable results in assays examining receptor-ligand interactions, peptide conformational dynamics, analytical quantification, and computational modeling
It is context for why the research momentum exists
However, despite promising preclinical results, the clinical translation of SIN is limited by its poor pharmacokinetic profile, including low oral bioavailability and rapid systemic clearance
10.1046/j.1469-7580.1999.19430335.x J
