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Nicotinamide adenine dinucleotide (NAD + ) is a vital cofactor in mitochondrial bioenergetic pathways, including glycolysis, fatty acid -oxidation, and the TCA cycle 517

Similar content being viewed by others Introduction Local chronic inflammation not only extends beyond a pathological state localized within specific tissues/organs, but also profoundly reshape systemic immunity through peripheral inflammatory signaling

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The results of the study demonstrated that miR-124-3p sEVs safeguard DA neurons from 6-OHDA-induced damage in both in vitro and in vivo models, ultimately leading to complete motor function recovery in vivo