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We next examined the effects of Fer-1 and ML162 in wildtype and gpx mutants

In some cells, ferroptosis acts as an active driver of tissue destruction, whereas in others, it represents a passive consequence or an accompanying phenomenon of the pathological environment

Leggio L., L'Episcopo F., and Magr A., Small Extracellular Vesicles Secreted by Nigrostriatal Astrocytes Rescue Cell Death and Preserve Mitochondrial Function in Parkinson's Disease, Adv Healthc Mater 11, no

There are many enzymes in the cells that can destroy ROS, which are mainly composed of superoxide dismutase (SOD), catalase (CAT), ascorbate peroxide (APX) and glutathion peroxidase (GPX)