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About the pathway by which p53 promotes ferroptosis, it could not only regulate the expression of the downstream proteins glutaminase 2 (GLS2) ( WAF1/Cip1 , CDKN1A/p21) ( 3 The role of ferroptosis in inflammatory arthritis Inflammatory arthritis refers to inflammatory diseases occurring in human joints and surrounding tissues caused by inflammation, infection, trauma, or other factors

While tryptophan may be deficient in individuals with ASD, supplementation with B vitamins and magnesium may influence tryptophan metabolic homeostasis [179]

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