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While it's true that genetic testing has been called into question, homocysteine remains a very good proxy for how well methylation is performing, and when levels rise too high, this can provide the skilled clinician valuable information to structure their treatment around to catch cardiovascular risk that is often missed with standard measurements and labs

Conclusion In the debate between lipotropic B12 injections and oral supplements, the best choice depends on individual needs, preferences, and medical advice

ATP7A-LINKED NEURODEGENERATIVE DISORDERS Unlike AT7B, where mutations in the gene result in a single known clinical phenotype (Wilson disease), mutations in ATP7A cause three X-linked neurodegenerative diseasesMenkes disease, occipital horn syndrome (OHS), and X-linked distal hereditary neuropathy (dHMN) (Kaler, 2011)

Dev Brain Res 153(1):111 Duerson K et al (2009) Detergent-insoluble EAAC1/EAAT3 aberrantly accumulates in hippocampal neurons of Alzheimers disease patients