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In L5 of rat insular cortex, paired recordings between nearby GABA neurons and other GABA neurons or pyramidal cells revealed the role of MOR in regulating these synapses (Yokota et al., 2016)

doi: 10.1016/0006-2952(91)90099-q

MPTP 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), a meperidine congener, was accidentally produced in the early 1980s during an impure synthesis of MPPP, which is an opioid analgesic drug (Davis et al., 1983)

Rotating sites may reduce irritation when multiple injections are needed
