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Research suggests that individuals with lupus may have lower levels of glutathione, which can contribute to the oxidative stress and inflammation commonly observed in the disease

Bocci, V., Luzzi, E., Corradeshi, F., Paulesu, L.,Di Stefano, A., Studies on the biological effects of ozone: 3

In other words, the high presence of PyroGlu contributes even further to GSH deficiency and would be an indicator of high oxidative stress
