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Description
While FOXO4 can influence mitochondrial function indirectly through its regulatory effects on cellular processes, it does not directly target mitochondria like the other mitochondria-targeted peptides listed above

"Metformin and Vitamin B12 Deficiency: Where Do We Stand?"

Hence, the downstream pathways are targeted for drug development

Reduced-calorie diet combined with NNMT inhibition normalizes liver pathologies vs diet alone
