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When cortisol-related symptoms persist despite lifestyle modificationincluding progressive central weight gain, easy bruising, proximal muscle weakness, wide purple striae, resistant hypertension, unexplained osteoporosis, or hypokalemiaformal endocrine evaluation is warranted to exclude pathological hypercortisolism requiring specialized intervention

Among all agonists, sCT was the least selective peptide towards the CTR, AMY 1 R or AMY 3 R

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Potentiation of pro-inflammatory cytokine suppression and survival by microencapsulated dexamethasone in the treatment of experimental sepsis