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According to their stress-inducible expression, it is documented that many GSTFs and GSTUs have functions connected to secondary metabolism, as exemplified by their implication in the vacuolar sequestration of anthocyanin, in the biosynthesis of camalexin, and/or in the binding of biosynthesis intermediates (porphyrin derivatives) or cellular by-products (oxylipins)

Aluminum (Al), cadmium (Cd), arsenic (As), mercury (Hg), lead (Pb), and chromium (Cr) and their roles in the development of gastrointestinal, pulmonary, kidney, reproductive, neurodegenerative (Alzheimers and Parkinsons diseases), cardiovascular, and cancer (e.g

550 In Phase II trials (KARDIA-1), zilebesiran reduced systolic blood pressure in all treated patients, with effects lasting 6 months, opening new possibilities for NADs use in treating hypertension and CVDs