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In the presence of high molecular weight procyanidins, however, it is apparently continuously produced by the activity of gut microbiota releasing catechin and epicatechin units from procyanidin oligomers and polymers (Figure 2) (32, 55)

Research published in the Journal of Cellular and Molecular Medicine demonstrated that consumption of hydrogen-rich water upregulated the expression of antioxidant enzymes, including glutathione reductase, in animal models of oxidative stress

SOD1 inhibitors, including ATN-224 and disulfiram, selectively enhance oxidative stress in tumor cells and are currently being tested in clinical trials

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