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[DOI] [PubMed] [Google Scholar] Huang JP, Hsu SC, Li DE, Chen KH, Kuo CY, Hung LM

Gallo D, Mortara L, Veronesi G, Cattaneo SA, Genoni A, Gallazzi M et al (2022) Add-On Effect of Selenium and Vitamin D Combined Supplementation in Early Control of Graves Disease Hyperthyroidism During Methimazole Treatment

It suppresses excessive reactive oxygen species (ROS) and maintains mitochondrial function by modulating the Receptor-Interacting Protein Kinase 3-Mixed Lineage Kinase Domain-Like protein (RIP3-MLKL) (necroptosis-related) and Receptor-Interacting Protein Kinase 1 (RIP1)-Nuclear-related factor 2 (Nrf2)-Nuclear Factor kappa-light-chain-enhancer of activated B cells (NF-B) (antioxidant/inflammatory) pathways, ultimately promoting cellular survival

Higher does not equal better - it equals more expensive and more side-effect prone