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19 AST controls the NAD+/NADH ratio in cells by taking part in the malate-aspartate shuttle in which NADH is oxidized

Most Cys oxidative PTMs are initiated by reactive oxygen or nitrogen species (ROS/RNS) or sulfane (H 2 S) reacting with the free thiol on a Cys side chain ( Figure 1A )

A GCLC responsable de toda a actividade encimtica, mentres que a GCLM acrecenta a eficiencia cataltica do GCLC