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Loguercio, C., Federico, A., Trappoliere, M., Tuccillo, C., Sio, I

This is to show some of the key cellular and molecular players against which it is conceivable to use old and new immunotherapeutic tools as antibodies or CAR-T cells to further improve the outcome of MB patients

Vitamin B12 therapy is considered to be rather safe, and hypersensitivity reactions have been described very rarely, usually after parenteral administration
However, edaravone causes hypersensitivity and allergic reactions in some patients and may be effective in less than 5% of the ALS population [Writing Group
