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Avoid treatment during pregnancy as there are no safety studies of Botox during pregnancy or breastfeeding
The pathogenesis of PD involves several interconnected processes centered on syn aggregation, dopaminergic neurodegeneration, and neuroinflammation
It also appears to reduce VEGF (vascular endothelial growth factor) expression (Li 2013), increase expression of the tumor suppressor protein p53, and inhibit COX-2 expression (Lu 2012)
