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To examine this possibility, we investigated the kinetics of the reaction under biological conditions and determined the second order rate constant k as 2.3600.198M1s1

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Chronic activation of inflammasome signaling in microglia and astrocytes, characterized by the upregulation of NLRP3 and NF-B, has been linked to the establishment of a neuroinflammatory environment, leading to synaptic loss and exacerbating tau pathology
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