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These mice also exhibit decreased phosphorylation of S6K1 on Thr389 (50%) and of 4E-BP1 (25%) when fed a low protein diet (Ishikawa et al., 2017)

Odle J, Adams SH, Vockley J

therefore, its prevention and treatment have gained increased attention among researchers

Future studies aiming to assess the duration of the therapeutic efficacy and the optimal dose in larger populations, possibly with longer follow-up periods, are required
