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A meta-analysis found a 14% death rate in these cases, and a 2025 JAMA Network Open study showed that infection risk jumps sharply after day 3 of catheter use, with an adjusted odds ratio of 13.55

13C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS) Proceedings of the National Academy of Sciences of the United States of America

For crystallization, it may require changing to fluorescent tag-free constructs so that the POI did not experience compositional shock during later purification steps

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