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This exceptional BBB permeability stems from its relatively small molecular weight of 750 Da and specific structural modifications that allow passive diffusion across endothelial tight junctions

Spermidine-mediated induction of autophagy requires that the pro-autophagic transcription factor identified as TFEB (transcription factor EB, where the EB refers to enhancer box binding site) be activated

Induction of hippocampal long-term potentiation during waking leads to increased extrahippocampal zif-268 expression during ensuing rapid-eye-movement sleep

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