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Peripheral clocks are known to have organ specificity with respect to their primary entraining signals
GSH, however, is rapidly hydrolysed by the hepatic enzyme -glutamyl transferase (GGT), which, in addition to the biological barriers of the GIT, accounts for its low oral bioavailability [18]

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In cancer cells, the use of glutamate-derived nitrogen for NEAA production may be favored in various types of cancer cells to preserve nitrogen for anabolic reactions 48 and may prevent apoptosis induced by ATF4 activation upon glutamine deprivation 6