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Description
Its knockdown led to the impairment of apoptosis and the antiproliferative effect of LCA
HGF/Met Pathway The mesenchymal epithelial transition (Met) factor receptor is a receptor tyrosine kinase (RTK) that is encoded by the MET protooncogene (9)
This combined approach validates experimental observations and accelerates discovery
It also compromises the efficacy of chemotherapeutics, particularly weak base drugs like doxorubicin and vincristine, through ion trapping that reduces their intracellular concentration and by increasing the efflux activity of the p-glycoprotein (99101)
