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The analogy sometimes used in the research literature: if endogenous GH release is like pressing both the accelerator (GHRH pathway) and releasing the brake (ghrelin pathway) simultaneously, the CJC/Ipamorelin combination approximates this dual-signal effect more closely than single-agent stimulation

Boyle, S.J

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Of these, glutamate acts as a main excitatory neurotransmitter in the central nervous system (Henter et al., 2021), and excitatory amino acids associated with Lactobacillus are discussed as key factors in anxiety-like behavior (Oroojzadeh et al., 2022)