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Individuals at risk of choline inadequacy Daily intake recommendations are higher during pregnancy and lactation (see The AI), placing pregnant and lactating individuals at increased risk of choline inadequacy (25, 26)

Also, free radicals can damage sperm DNA through oxidation of purine and pyrimidine bases, breakage of DNA single and double strands, protamine deficiency, chromosomal rearrangement and gene mutation and the detrimental consequences are cell damage, cell apoptosis, and impaired fetus development

These units run a multidisciplinary clinic for children with DRE which means failure of two or more well selected and proper dosed AED to achieve sustained seizure freedom 2

Speir M, Tye H, Gottschalk TA, Simpson DS, Djajawi TM, Deo P