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Description
It consists of four protein subunits, each probably containing a single manganese atom

GPX3 is abundantly expressed in the kidneys, synthesized specifically in renal tubular cells and released into circulation or bound to tubular basement membranes [16]

& Eckhart, A
Depending on the type of cancer and stage, this can include hypoxia-related ROS functions and signalling pathways such as PI3K/AKT or MAPK/ERK pathways, among others, to promote proliferation, migration, or angiogenesis
