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In the pancreas, vagal efferents drive exocrine secretion (Mussa and Verberne 2008), and experimental studies have shown that VNS can elicit robust pancreatic secretion of digestive enzymes in rats (Wisdom et al

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The most abundant flavonoids are wogonin (5,7-dihydroxy-8-methoxyflavone), wogonoside (Wogonin-7-glucuronic acid), baicalin (7-glucuronic acid, 5,6-dihydroxy-flavone) and baicalein, of which the therapeutic values mainly lie in its therapeutic effects in various liver diseases including hepatitis, cirrhosis and liver cancer (Zhao et al., 2006)