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Two animal studies, analysing the effect of TP508 loaded on PPF composite and microsphere scaffolds on segmental bone defects in rabbits, showed enhanced bone formation with a higher torsional stiffness of bone [99, 101]

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Neurodegener Dis 5(34):225227 Pi Y et al (2012) Lack of an association between paraoxonase 1 gene polymorphisms (Q192R, L55M) and Alzheimers disease: a meta-analysis
