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Drugs used to prevent migraines include blood pressure medications (e.g., beta blockers, calcium channel blockers, ACE inhibitors, and angiotensin receptor blockers), tricyclic antidepressants (e.g., amitriptyline [Elavil]), and anticonvulsants (e.g., valproate [Depakote], gabapentin [Neurontin], and topiramate [Topamax])
Researchers continue to study how these signaling pathways influence tissue physiology, cellular adaptation, vascular biology, and molecular communication under controlled laboratory conditions
In a separate study conducted by Lukyanova et al., emoxypine succinate was observed to exert an anti-ischemic action in the rat brain and ischemic myocardium by increasing the coupling of oxidative phosphorylation and mitochondrial respiration
* Correspondence: Ying Liang, [email protected]
