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This happens because certain MTHFR mutations (C667T and A129C) lower the amount of active folate being produced in the body, and the use of vitamin B12 requires the active form of folate

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Its found in animal products such as dairy products, eggs, fish, and chicken, as well as fortified cereals and nutritional yeast

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Additionally, all PCR amplicons were selected for sequencing

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Legislative proposals to change this exclusion have been introduced but have not passed as of early 2026

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