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QikProp predicts the ability of specific molecules to cross the BBB (Table 2)
Cuproptosis is based on the direct binding of copper ions to lipoylase proteins in the tricarboxylic acid cycle, leading to abnormal aggregation (174)
doi: 10.1152/ajpendo.2001.280.2.E221 44 TrendelenburgAUMeyerARohnerDBoyleJHatakeyamaSGlassDJ
The disruption of this balance can be linked to the production of excessive quantities of oxidizing molecules or to the inefficiency of antioxidant systems
