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The liver is responsible for the metabolism of various compounds, with the resultant production of reactive oxygen radicals ( 11 )

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Retrochalcone Echinatin Triggers Apoptosis of Esophageal Squamous Cell Carcinoma via ROS- and ER Stress-Mediated Signaling Pathways

This had never been done before because it has been very difficult and laborious to obtain the pure enzymes, but this study was now enabled by our recent method development to produce recombinant selenoproteins with internal Sec residues, such as the GPX isoenzymes