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P values of less than 0.05 were considered significant

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Reconstitution 3-step visual Reconstitute , add bacteriostatic water down the wall of the vial Measure , use the calculator (section 8) to compute the required volume Store , refrigerator 2 to 8 C, strictly protect from light Detailed protocol What you will need: A vial of GHK-Cu (50 mg blue lyophilizate) 5 ml of bacteriostatic water (0.9 % benzyl alcohol) Insulin syringe 1 ml / 29G Dim work environment (if possible) Procedure: Allow the vial of GHK-Cu to reach room temperature (15 to 20 min)

This poses significant challenges for the long-term success of gene therapy, mainly in patients receiving low doses of AAV, such as children, as tissue growth and proliferation may dilute the vector genome, potentially worsening symptoms over time